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SQSTM1/p62 (sequestosome 1) senses cellular ubiquitin stress through E2-mediated ubiquitination

The alterations in cellular ubiquitin (Ub) homeostasis, known as Ub stress, feature and affect cellular responses in multiple conditions, yet the underlying mechanisms are incompletely understood. We recently reported that the macroautophagy/autophagy receptor SQSTM1/p62, functions as a novel Ub sen...

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Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Yang, Jiao, Peng, Hong, Xu, Yumin, Xie, Xiaoduo, Hu, Ronggui
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103393/
https://ncbi.nlm.nih.gov/pubmed/28614034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1332566
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