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Autophagy substrate SQSTM1/p62 regulates chromatin ubiquitination during the DNA damage response
The importance of autophagy in the DNA damage repair process is clear; however, the detailed molecular mechanism is still largely unknown. Here we found that DNA damage-induced histone H2A ubiquitination is suppressed in autophagy-deficient cells in a SQSTM1/p62 dependent manner. SQSTM1 binds and in...
Shranjeno v:
| izdano v: | Autophagy |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240823/ https://ncbi.nlm.nih.gov/pubmed/27791533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1245262 |
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