Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice

Cav1.2 is the pore‐forming subunit of L‐type voltage‐gated calcium channel (LTCC) that plays an important role in calcium overload and cell death in Alzheimer's disease. LTCC activity can be regulated by estrogen, a sex steroid hormone that is neuroprotective. Here, we investigated the potentia...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Lai, Yu‐Jie, Zhu, Bing‐Lin, Sun, Fei, Luo, Dong, Ma, Yuan‐Lin, Luo, Bio, Tang, Jing, Xiong, Ming‐Jian, Liu, Lu, Long, Yan, Hu, Xiao‐Tong, He, Ling, Deng, Xiao‐Juan, Zhang, John H., Yang, Jian, Yan, Zhen, Chen, Guo‐Jun
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612642/
https://ncbi.nlm.nih.gov/pubmed/31012223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12961
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker