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Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice
The aging brain with mitochondrial dysfunction and a reduced adenosine 5’-triphosphate (ATP) has been implicated in the onset and progression of β-Amyloid (Aβ)-induced neuronal toxicity in AD. To unravel the function of ATP and the underlying mechanisms on AD development, APP/PS1 double transgenic m...
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| Published in: | Aging (Albany NY) |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6914425/ https://ncbi.nlm.nih.gov/pubmed/31744937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102451 |
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