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Evolution of protein kinase substrate recognition at the active site

Protein kinases catalyse the phosphorylation of target proteins, controlling most cellular processes. The specificity of serine/threonine kinases is partly determined by interactions with a few residues near the phospho-acceptor residue, forming the so-called kinase-substrate motif. Kinases have bee...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Bradley, David, Beltrao, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611643/
https://ncbi.nlm.nih.gov/pubmed/31233486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000341
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