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Benchmarking substrate-based kinase activity inference using phosphoproteomic data

MOTIVATION: Phosphoproteomic experiments are increasingly used to study the changes in signaling occurring across different conditions. It has been proposed that changes in phosphorylation of kinase target sites can be used to infer when a kinase activity is under regulation. However, these approach...

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Publicat a:Bioinformatics
Autors principals: Hernandez-Armenta, Claudia, Ochoa, David, Gonçalves, Emanuel, Saez-Rodriguez, Julio, Beltrao, Pedro
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870625/
https://ncbi.nlm.nih.gov/pubmed/28200105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx082
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