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Benchmarking substrate-based kinase activity inference using phosphoproteomic data

MOTIVATION: Phosphoproteomic experiments are increasingly used to study the changes in signaling occurring across different conditions. It has been proposed that changes in phosphorylation of kinase target sites can be used to infer when a kinase activity is under regulation. However, these approach...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Hernandez-Armenta, Claudia, Ochoa, David, Gonçalves, Emanuel, Saez-Rodriguez, Julio, Beltrao, Pedro
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870625/
https://ncbi.nlm.nih.gov/pubmed/28200105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx082
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