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Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

MAP kinases phosphorylate specific groups of substrate proteins. Here we show that the amino acid sequence FXFP is an evolutionarily conserved docking site that mediates ERK MAP kinase binding to substrates in multiple protein families. FXFP and the D box, a different docking site, form a modular re...

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Detalhes bibliográficos
Main Authors: Jacobs, Dave, Glossip, Danielle, Xing, Heming, Muslin, Anthony J., Kornfeld, Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316390/
https://ncbi.nlm.nih.gov/pubmed/9925641
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