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Examining Docking Interactions on ERK2 with Modular Peptide Substrates
ERK2 primarily recognizes substrates through two recruitment sites, which lie outside the active site cleft of the kinase. These recruitment sites bind modular-docking sequences called docking sites and are potentially attractive sites for the development of non-ATP competitive inhibitors. The D-rec...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422614/ https://ncbi.nlm.nih.gov/pubmed/21955038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201103b |
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