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Understanding the Specificity of a Docking Interaction between JNK1 and the Scaffolding Protein JIP1
The up-regulation of JNK activity is associated with a number of disease states. The JNK-JIP1 interaction represents an attractive target for the inhibition of JNK-mediated signaling. In this study, molecular dynamics simulations have been performed on the apo-JNK1, and the JNK1•L-pepJIP1 and JNK1•D...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042137/ https://ncbi.nlm.nih.gov/pubmed/21261310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp1073522 |
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