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The CRAL/TRIO and GOLD Domain Protein CGR-1 Promotes Induction of Vulval Cell Fates in Caenorhabditis elegans and Interacts Genetically With the Ras Signaling Pathway

Ras-mediated signaling is necessary for the induction of vulval cell fates during Caenorhabditis elegans development. We identified cgr-1 by screening for suppressors of the ectopic vulval cell fates caused by a gain-of-function mutation of the let-60 ras gene. Analysis of two cgr-1 loss-of-function...

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Autors principals: Goldstein, Jessica L., Glossip, Danielle, Nayak, Sudhir, Kornfeld, Kerry
Format: Artigo
Idioma:Inglês
Publicat: Copyright © 2006 by the Genetics Society of America 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456255/
https://ncbi.nlm.nih.gov/pubmed/16219793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.035550
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