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Intercellular coupling amplifies fate segregation during Caenorhabditis elegans vulval development

During vulval development in Caenorhabditis elegans, six precursor cells acquire a spatial pattern of distinct cell fates. This process is guided by a gradient in the soluble factor, LIN-3, and by direct interactions between neighboring cells mediated by the Notch-like receptor, LIN-12. Genetic evid...

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Hlavní autoři: Giurumescu, Claudiu A., Sternberg, Paul W., Asthagiri, Anand R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360524/
https://ncbi.nlm.nih.gov/pubmed/16432231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506476103
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