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Distal Recognition Sites in Substrates Are Required for Efficient Phosphorylation by the cAMP-Dependent Protein Kinase

Protein kinases are important mediators of signal transduction in eukaryotic cells, and identifying the substrates of these enzymes is essential for a complete understanding of most signaling networks. In this report, novel substrate-binding variants of the cAMP-dependent protein kinase (PKA) were u...

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Detalhes bibliográficos
Main Authors: Deminoff, Stephen J., Ramachandran, Vidhya, Herman, Paul K.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691761/
https://ncbi.nlm.nih.gov/pubmed/19364808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.102178
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