DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program

The molecular mechanism controlling the zygotic genome activation (ZGA) in mammals remains poorly understood. The 2-cell (2C)-like cells spontaneously emerging from cultures of mouse embryonic stem cells (ESCs) share some key transcriptional and epigenetic programs with 2C-stage embryos. By studying...

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Publicat a:PLoS Biol
Autors principals: Yan, Yao-Long, Zhang, Chao, Hao, Jing, Wang, Xue-Lian, Ming, Jia, Mi, Li, Na, Jie, Hu, Xinli, Wang, Yangming
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608977/
https://ncbi.nlm.nih.gov/pubmed/31226106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000324
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