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DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program
The molecular mechanism controlling the zygotic genome activation (ZGA) in mammals remains poorly understood. The 2-cell (2C)-like cells spontaneously emerging from cultures of mouse embryonic stem cells (ESCs) share some key transcriptional and epigenetic programs with 2C-stage embryos. By studying...
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| Publicado no: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608977/ https://ncbi.nlm.nih.gov/pubmed/31226106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000324 |
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