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Assessment of the Stability of Supraphysiological Ascorbate in Human Blood: Appropriate Handling of Samples from Clinical Trials for Measurements of Pharmacological Ascorbate

Based on encouraging results from several early-phase clinical trials, there is renewed interest in the use of pharmacological ascorbate (i.e., intravenous administration resulting in .> ≈ 10 mM plasma ascorbate concentrations) in combination with standard-of-care cancer treatments including radi...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Petronek, Michael S., Wagner, Brett A., Hollenbeck, Nancy J., Caster, Joseph M., Spitz, Douglas R., Cullen, Joseph J., Buettner, Garry R., Allen, Bryan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608566/
https://ncbi.nlm.nih.gov/pubmed/31039080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15328.1
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