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Genetic or Pharmacological Reduction of PERK Enhances Cortical-Dependent Taste Learning

Protein translation initiation is controlled by levels of eIF2α phosphorylation (p-eIF2α) on Ser51. In addition, increased p-eIF2α levels impair long-term synaptic plasticity and memory consolidation, whereas decreased levels enhance them. Levels of p-eIF2α are determined by four kinases, of which p...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Ounallah-Saad, Hadile, Sharma, Vijendra, Edry, Efrat, Rosenblum, Kobi
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608429/
https://ncbi.nlm.nih.gov/pubmed/25355215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2117-14.2014
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