Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties

Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is one of four known kinases that respond to cellular stress by deactivating the eukaryotic initiation factor 2 α (eIF2α) or other signal transduction cascades. Recently, both eIF2α and its kinases were found to play a role in normal an...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sharma, Vijendra, Ounallah-Saad, Hadile, Chakraborty, Darpan, Hleihil, Mohammad, Sood, Rapita, Barrera, Iliana, Edry, Efrat, Kolatt Chandran, Sailendrakumar, Ben Tabou de Leon, Shlomo, Kaphzan, Hanoch, Rosenblum, Kobi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596193/
https://ncbi.nlm.nih.gov/pubmed/29196323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0628-17.2017
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