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Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination

The mammalian target of rapamycin (mTOR) pathway integrates multiple signals and regulates crucial cell functions via the molecular complexes mTORC1 and mTORC2. These complexes are functionally dependent on their raptor (mTORC1) or rictor (mTORC2) subunits. mTOR has been associated with oligodendroc...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Lebrun-Julien, Frédéric, Bachmann, Lea, Norrmén, Camilla, Trötzmüller, Martin, Köfeler, Harald, Rüegg, Markus A., Hall, Michael N., Suter, Ueli
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608214/
https://ncbi.nlm.nih.gov/pubmed/24948799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1105-14.2014
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