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Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination

The mammalian target of rapamycin (mTOR) pathway integrates multiple signals and regulates crucial cell functions via the molecular complexes mTORC1 and mTORC2. These complexes are functionally dependent on their raptor (mTORC1) or rictor (mTORC2) subunits. mTOR has been associated with oligodendroc...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lebrun-Julien, Frédéric, Bachmann, Lea, Norrmén, Camilla, Trötzmüller, Martin, Köfeler, Harald, Rüegg, Markus A., Hall, Michael N., Suter, Ueli
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608214/
https://ncbi.nlm.nih.gov/pubmed/24948799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1105-14.2014
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