Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination

Myelin abnormalities are increasingly being recognized as an important component of a number of neurologic developmental disorders. The integration of many signaling pathways and cell types are critical for correct myelinogenesis. The PI3-K and mechanistic target of rapamycin (mTOR) pathways have be...

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Publicat a:PLoS One
Autors principals: Grier, Mark D., West, Kathryn L., Kelm, Nathaniel D., Fu, Cary, Does, Mark D., Parker, Brittany, McBrier, Eleanor, Lagrange, Andre H., Ess, Kevin C., Carson, Robert P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697806/
https://ncbi.nlm.nih.gov/pubmed/29161318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188417
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