Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination

The mammalian target of rapamycin (mTOR) pathway integrates multiple signals and regulates crucial cell functions via the molecular complexes mTORC1 and mTORC2. These complexes are functionally dependent on their raptor (mTORC1) or rictor (mTORC2) subunits. mTOR has been associated with oligodendroc...

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Publicat a:J Neurosci
Autors principals: Lebrun-Julien, Frédéric, Bachmann, Lea, Norrmén, Camilla, Trötzmüller, Martin, Köfeler, Harald, Rüegg, Markus A., Hall, Michael N., Suter, Ueli
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608214/
https://ncbi.nlm.nih.gov/pubmed/24948799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1105-14.2014
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