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Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination

The mammalian target of rapamycin (mTOR) pathway integrates multiple signals and regulates crucial cell functions via the molecular complexes mTORC1 and mTORC2. These complexes are functionally dependent on their raptor (mTORC1) or rictor (mTORC2) subunits. mTOR has been associated with oligodendroc...

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Pubblicato in:J Neurosci
Autori principali: Lebrun-Julien, Frédéric, Bachmann, Lea, Norrmén, Camilla, Trötzmüller, Martin, Köfeler, Harald, Rüegg, Markus A., Hall, Michael N., Suter, Ueli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608214/
https://ncbi.nlm.nih.gov/pubmed/24948799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1105-14.2014
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