Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors

OBJECTIVE: While abnormalities in myelin in tuberous sclerosis complex (TSC) have been known for some time, recent imaging‐based data suggest myelin abnormalities may be independent of the pathognomonic cortical lesions (“tubers”). Multiple mouse models of TSC exhibit myelination deficits, though th...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Carson, Robert P., Kelm, Nathaniel D., West, Kathryn L., Does, Mark D., Fu, Cary, Weaver, Grace, McBrier, Eleanor, Parker, Brittany, Grier, Mark D., Ess, Kevin C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693589/
https://ncbi.nlm.nih.gov/pubmed/26734657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.254
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