Alcohol‐induced miR‐155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

Inflammation promotes the progression of alcoholic liver disease. Alcohol sensitizes KCs to gut‐derived endotoxin (LPS); however, signaling pathways that perpetuate inflammation in alcoholic liver disease are only partially understood. We found that chronic alcohol feeding in mice induced miR‐155, a...

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Detaylı Bibliyografya
Yayımlandı:J Leukoc Biol
Asıl Yazarlar: Bala, Shashi, Csak, Timea, Kodys, Karen, Catalano, Donna, Ambade, Aditya, Furi, Istvan, Lowe, Patrick, Cho, Yeonhee, Iracheta‐Vellve, Arvin, Szabo, Gyongyi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608073/
https://ncbi.nlm.nih.gov/pubmed/28584078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0716-310R
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