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Interferon‐inducible guanylate‐binding proteins at the interface of cell‐autonomous immunity and inflammasome activation

Guanylate‐binding proteins (GBPs) are essential components of cell‐autonomous immunity. In response to IFN signaling, GBPs are expressed in the cytoplasm of immune and nonimmune cells, where they unleash their antimicrobial activity toward intracellular bacteria, viruses, and parasites. Recent studi...

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Библиографические подробности
Опубликовано в: :J Leukoc Biol
Главные авторы: Man, Si Ming, Place, David E., Kuriakose, Teneema, Kanneganti, Thirumala‐Devi
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608036/
https://ncbi.nlm.nih.gov/pubmed/27418355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4MR0516-223R
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