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Interferon‐inducible guanylate‐binding proteins at the interface of cell‐autonomous immunity and inflammasome activation

Guanylate‐binding proteins (GBPs) are essential components of cell‐autonomous immunity. In response to IFN signaling, GBPs are expressed in the cytoplasm of immune and nonimmune cells, where they unleash their antimicrobial activity toward intracellular bacteria, viruses, and parasites. Recent studi...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Man, Si Ming, Place, David E., Kuriakose, Teneema, Kanneganti, Thirumala‐Devi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608036/
https://ncbi.nlm.nih.gov/pubmed/27418355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4MR0516-223R
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