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Regulation and functions of NLRP3 inflammasome during influenza virus infection

The NLRP3 inflammasome constitutes a major antiviral host defense mechanism during influenza virus infection. Inflammasome assembly in virus-infected cells facilitates autocatalytic processing of pro-caspase-1 and subsequent cleavage and secretion of proinflammatory cytokines IL-1β and IL-18. The NL...

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Bibliografski detalji
Izdano u:Mol Immunol
Glavni autori: Kuriakose, Teneema, Kanneganti, Thirumala-Devi
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453821/
https://ncbi.nlm.nih.gov/pubmed/28169000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.01.023
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