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IRF1 is a transcriptional regulator of ZBP1 promoting NLRP3 inflammasome activation and cell death during influenza virus infection

Innate immune sensing of influenza A virus (IAV) induces activation of various immune effector mechanisms including the NLRP3 inflammasome and programmed cell death pathways. Although type I IFNs are identified as key mediators of inflammatory and cell death responses during IAV infection, the invol...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Kuriakose, Teneema, Zheng, Min, Neale, Geoffrey, Kanneganti, Thirumala-Devi
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483084/
https://ncbi.nlm.nih.gov/pubmed/29321274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701538
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