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ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death
Innate sensing of influenza virus infection induces activation of programmed cell death pathways. We have recently identified Z-DNA–binding protein 1 (ZBP1) as an innate sensor of influenza A virus (IAV). ZBP1-mediated IAV sensing is critical for triggering programmed cell death in the infected lung...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551577/ https://ncbi.nlm.nih.gov/pubmed/28634194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170550 |
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