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Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis

Caspases are a family of conserved cysteine proteases that play key roles in programmed cell death and inflammation. In multicellular organisms, caspases are activated via macromolecular signaling complexes that bring inactive procaspases together and promote their proximity-induced autoactivation a...

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Bibliografske podrobnosti
izdano v:Annu Rev Immunol
Main Authors: Kesavardhana, Sannula, Malireddi, R.K. Subbarao, Kanneganti, Thirumala-Devi
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190443/
https://ncbi.nlm.nih.gov/pubmed/32017655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-073119-095439
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