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Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways

Hepatocellular carcinoma (HCC) is the fourth largest cause of cancer-related deaths worldwide with limited therapeutic interventions. Renewed interest in natural products as drug leads has resulted in a paradigm shift toward the rapid screening of medicinal plants for the discovery of new chemical e...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Roy, Gaurab, Guan, Su, Liu, Hexiang, Zhang, Lei
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606729/
https://ncbi.nlm.nih.gov/pubmed/31293977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00545
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