CtIP is essential for early B cell proliferation and development in mice

B cell development requires efficient proliferation and successful assembly and modifications of the immunoglobulin gene products. CtIP is an essential gene implicated in end resection and DNA repair. Here, we show that CtIP is essential for early B cell development but dispensable in naive B cells....

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Liu, Xiangyu, Wang, Xiaobin S., Lee, Brian J., Wu-Baer, Foon K., Lin, Xiaohui, Shao, Zhengping, Estes, Verna M., Gautier, Jean, Baer, Richard, Zha, Shan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2019
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605744/
https://ncbi.nlm.nih.gov/pubmed/31097467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181139
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