CtIP is essential for early B cell proliferation and development in mice

B cell development requires efficient proliferation and successful assembly and modifications of the immunoglobulin gene products. CtIP is an essential gene implicated in end resection and DNA repair. Here, we show that CtIP is essential for early B cell development but dispensable in naive B cells....

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Liu, Xiangyu, Wang, Xiaobin S., Lee, Brian J., Wu-Baer, Foon K., Lin, Xiaohui, Shao, Zhengping, Estes, Verna M., Gautier, Jean, Baer, Richard, Zha, Shan
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605744/
https://ncbi.nlm.nih.gov/pubmed/31097467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181139
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