CtIP is essential for early B cell proliferation and development in mice

B cell development requires efficient proliferation and successful assembly and modifications of the immunoglobulin gene products. CtIP is an essential gene implicated in end resection and DNA repair. Here, we show that CtIP is essential for early B cell development but dispensable in naive B cells....

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Liu, Xiangyu, Wang, Xiaobin S., Lee, Brian J., Wu-Baer, Foon K., Lin, Xiaohui, Shao, Zhengping, Estes, Verna M., Gautier, Jean, Baer, Richard, Zha, Shan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605744/
https://ncbi.nlm.nih.gov/pubmed/31097467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181139
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