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CtIP is essential for early B cell proliferation and development in mice
B cell development requires efficient proliferation and successful assembly and modifications of the immunoglobulin gene products. CtIP is an essential gene implicated in end resection and DNA repair. Here, we show that CtIP is essential for early B cell development but dispensable in naive B cells....
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| Veröffentlicht in: | J Exp Med |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605744/ https://ncbi.nlm.nih.gov/pubmed/31097467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181139 |
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