CtIP is essential for early B cell proliferation and development in mice

B cell development requires efficient proliferation and successful assembly and modifications of the immunoglobulin gene products. CtIP is an essential gene implicated in end resection and DNA repair. Here, we show that CtIP is essential for early B cell development but dispensable in naive B cells....

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Liu, Xiangyu, Wang, Xiaobin S., Lee, Brian J., Wu-Baer, Foon K., Lin, Xiaohui, Shao, Zhengping, Estes, Verna M., Gautier, Jean, Baer, Richard, Zha, Shan
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2019
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605744/
https://ncbi.nlm.nih.gov/pubmed/31097467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181139
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