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Probing the Link among Genomic Cargo, Contact Mechanics, and Nanoindentation in Recombinant Adeno-Associated Virus 2

Recombinant adeno-associated virus (AAV) is a promising gene therapy vector. To make progress in this direction, the relationship between the characteristics of the genomic cargo and the capsid stability must be understood in detail. The goal of this study is to determine the role of the packaged ve...

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Foilsithe in:J Phys Chem B
Main Authors: Zeng, Cheng, Moller-Tank, Sven, Asokan, Aravind, Dragnea, Bogdan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604837/
https://ncbi.nlm.nih.gov/pubmed/28142241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b10131
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