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Probing the Link among Genomic Cargo, Contact Mechanics, and Nanoindentation in Recombinant Adeno-Associated Virus 2

Recombinant adeno-associated virus (AAV) is a promising gene therapy vector. To make progress in this direction, the relationship between the characteristics of the genomic cargo and the capsid stability must be understood in detail. The goal of this study is to determine the role of the packaged ve...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Zeng, Cheng, Moller-Tank, Sven, Asokan, Aravind, Dragnea, Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604837/
https://ncbi.nlm.nih.gov/pubmed/28142241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b10131
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