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Terminal N-Linked Galactose Is the Primary Receptor for Adeno-associated Virus 9
Sialylated glycans serve as cell surface attachment factors for a broad range of pathogens. We report an atypical example, where desialylation increases cell surface binding and infectivity of adeno-associated virus (AAV) serotype 9, a human parvovirus isolate. Enzymatic removal of sialic acid, but...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075699/ https://ncbi.nlm.nih.gov/pubmed/21330365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210922 |
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