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Glycan Binding Avidity Determines the Systemic Fate of Adeno-Associated Virus Type 9

Glycans are key determinants of host range and transmissibility in several pathogens. In the case of adeno-associated viruses (AAV), different carbohydrates serve as cellular receptors in vitro; however, their contributions in vivo are less clear. A particularly interesting example is adeno-associat...

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Detalhes bibliográficos
Main Authors: Shen, Shen, Bryant, Kelli D., Sun, Junjiang, Brown, Sarah M., Troupes, Andrew, Pulicherla, Nagesh, Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457279/
https://ncbi.nlm.nih.gov/pubmed/22787229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01155-12
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