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Multiple Roles for Sialylated Glycans in Determining the Cardiopulmonary Tropism of Adeno-Associated Virus 4

Adeno-associated virus 4 (AAV4) is one of the most divergent serotypes among known AAV isolates. Mucins or O-linked sialoglycans have been identified as the primary attachment receptors for AAV4 in vitro. However, little is known about the role(s) played by sialic acid interactions in determining AA...

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Détails bibliographiques
Auteurs principaux: Shen, Shen, Troupes, Andrew N., Pulicherla, Nagesh, Asokan, Aravind
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838263/
https://ncbi.nlm.nih.gov/pubmed/24067974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02109-13
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