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Unique Glycan Signatures Regulate Adeno-Associated Virus Tropism in the Developing Brain

Adeno-associated viruses (AAV) are thought to spread through the central nervous system (CNS) by exploiting cerebrospinal fluid (CSF) flux and hijacking axonal transport pathways. The role of host receptors that mediate these processes is not well understood. In the current study, we utilized AAV se...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Murlidharan, Giridhar, Corriher, Travis, Ghashghaei, H. Troy, Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403422/
https://ncbi.nlm.nih.gov/pubmed/25631075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02951-14
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