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Unique Glycan Signatures Regulate Adeno-Associated Virus Tropism in the Developing Brain

Adeno-associated viruses (AAV) are thought to spread through the central nervous system (CNS) by exploiting cerebrospinal fluid (CSF) flux and hijacking axonal transport pathways. The role of host receptors that mediate these processes is not well understood. In the current study, we utilized AAV se...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Murlidharan, Giridhar, Corriher, Travis, Ghashghaei, H. Troy, Asokan, Aravind
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403422/
https://ncbi.nlm.nih.gov/pubmed/25631075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02951-14
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