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Unique Glycan Signatures Regulate Adeno-Associated Virus Tropism in the Developing Brain

Adeno-associated viruses (AAV) are thought to spread through the central nervous system (CNS) by exploiting cerebrospinal fluid (CSF) flux and hijacking axonal transport pathways. The role of host receptors that mediate these processes is not well understood. In the current study, we utilized AAV se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Murlidharan, Giridhar, Corriher, Travis, Ghashghaei, H. Troy, Asokan, Aravind
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403422/
https://ncbi.nlm.nih.gov/pubmed/25631075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02951-14
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