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Fluorine-containing substituents: metabolism of the α,α-difluoroethyl thioether motif
We report the metabolism of the recently introduced α,α-difluoroethyl thioether motif to explore further its potential as a substituent for bioactives discovery chemistry. Incubation of two aryl–SCF(2)CH(3) ethers with the model yeast organism Cunninghamella elegans, indicates that the sulfur of the...
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| Publicat a: | Beilstein J Org Chem |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Beilstein-Institut
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604701/ https://ncbi.nlm.nih.gov/pubmed/31293694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.144 |
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