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Development and In Vivo Evaluation of a κ-Opioid Receptor Agonist as a PET Radiotracer with Superior Imaging Characteristics
Studies have shown κ-opioid receptor (KOR) abnormalities in addictive disorders, other central nervous system diseases, and Alzheimer’s disease. We have developed the first set of agonist (11)C-GR103545 and antagonist (11)C-LY2795050 radiotracers for PET imaging of KOR in humans. Nonetheless, (11)C-...
Tallennettuna:
| Julkaisussa: | J Nucl Med |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Society of Nuclear Medicine
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604690/ https://ncbi.nlm.nih.gov/pubmed/30630942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.220517 |
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