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Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

The maintenance of the homeostasis of immunoglobulin G (IgG) represents a fundamental aspect of humoral immunity that has direct relevance to the successful delivery of antibody-based therapeutics. The ubiquitously expressed neonatal Fc receptor (FcRn) salvages IgG from cellular degradation followin...

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Bibliografske podrobnosti
izdano v:MAbs
Main Authors: Challa, Dilip K., Wang, Xiaoli, Montoyo, Héctor Pérez, Velmurugan, Ramraj, Ober, Raimund J., Ward, E. Sally
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601554/
https://ncbi.nlm.nih.gov/pubmed/30964743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1602459
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