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Macrophage-mediated trogocytosis leads to death of antibody-opsonized tumor cells

Understanding the complex behavior of effector cells such as monocytes or macrophages in regulating cancerous growth is of central importance for cancer immunotherapy. Earlier studies using CD20-specific antibodies have demonstrated that the Fcγ receptor (FcγR)-mediated transfer of the targeted rece...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Velmurugan, Ramraj, Challa, Dilip K., Ram, Sripad, Ober, Raimund J., Ward, E. Sally
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975628/
https://ncbi.nlm.nih.gov/pubmed/27226489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0335
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