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Targeting FcRn for therapy: from live cell imaging to in vivo studies in mice

The role of FcRn in regulating antibody levels and transport in the body is well documented. The use of fluorescence microscopy to investigate the subcellular trafficking behavior of FcRn and its IgG ligand has led to insight into the function of this receptor, including the identification of new in...

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Dettagli Bibliografici
Autori principali: Ward, E. Sally, Velmurugan, Ramraj, Ober, Raimund J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058420/
https://ncbi.nlm.nih.gov/pubmed/24572175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2014.02.008
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