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Targeting FcRn to generate antibody-based therapeutics

The major histocompatibility complex (MHC) Class I-related receptor, FcRn, serves multiple roles ranging from the regulation of levels of IgG isotype antibodies and albumin throughout the body to delivery of antigen into antigen loading compartments in specialized antigen presenting cells. In parall...

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Bibliografiske detaljer
Udgivet i:Trends Pharmacol Sci
Main Authors: Ward, E. Sally, Ober, Raimund J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169532/
https://ncbi.nlm.nih.gov/pubmed/30143244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.07.007
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