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Targeting FcRn to generate antibody-based therapeutics
The major histocompatibility complex (MHC) Class I-related receptor, FcRn, serves multiple roles ranging from the regulation of levels of IgG isotype antibodies and albumin throughout the body to delivery of antigen into antigen loading compartments in specialized antigen presenting cells. In parall...
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| Published in: | Trends Pharmacol Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6169532/ https://ncbi.nlm.nih.gov/pubmed/30143244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.07.007 |
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