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FcRn blockade by Fc engineering ameliorates arthritis in a murine model

Multiple autoimmune diseases are characterized by the involvement of autoreactive antibodies in pathogenesis. Problems associated with existing therapeutics such as the delivery of intravenous immunoglobulin (IVIG) have led to interest in developing alternative approaches using recombinant or synthe...

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Detalhes bibliográficos
Main Authors: Patel, Dipesh A., Cantó, Alberto Puig, Challa, Dilip Kumar, Montoyo, Héctor Pérez, Ober, Raimund J., Ward, E. Sally
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157913/
https://ncbi.nlm.nih.gov/pubmed/21690327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003780
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