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FcRn blockade by Fc engineering ameliorates arthritis in a murine model
Multiple autoimmune diseases are characterized by the involvement of autoreactive antibodies in pathogenesis. Problems associated with existing therapeutics such as the delivery of intravenous immunoglobulin (IVIG) have led to interest in developing alternative approaches using recombinant or synthe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157913/ https://ncbi.nlm.nih.gov/pubmed/21690327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003780 |
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