TGIF1 functions as a tumor suppressor in pancreatic ductal adenocarcinoma

A prominent function of TGIF1 is suppression of transforming growth factor beta (TGF‐β) signaling, whose inactivation is deemed instrumental to the progression of pancreatic ductal adenocarcinoma (PDAC), as exemplified by the frequent loss of the tumor suppressor gene SMAD4 in this malignancy. Surpr...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Parajuli, Parash, Singh, Purba, Wang, Zhe, Li, Lianna, Eragamreddi, Sailaja, Ozkan, Seval, Ferrigno, Olivier, Prunier, Celine, Razzaque, Mohammed S, Xu, Keli, Atfi, Azeddine
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601038/
https://ncbi.nlm.nih.gov/pubmed/31268604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101067
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