TGIF1 functions as a tumor suppressor in pancreatic ductal adenocarcinoma

A prominent function of TGIF1 is suppression of transforming growth factor beta (TGF‐β) signaling, whose inactivation is deemed instrumental to the progression of pancreatic ductal adenocarcinoma (PDAC), as exemplified by the frequent loss of the tumor suppressor gene SMAD4 in this malignancy. Surpr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Parajuli, Parash, Singh, Purba, Wang, Zhe, Li, Lianna, Eragamreddi, Sailaja, Ozkan, Seval, Ferrigno, Olivier, Prunier, Celine, Razzaque, Mohammed S, Xu, Keli, Atfi, Azeddine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601038/
https://ncbi.nlm.nih.gov/pubmed/31268604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101067
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