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TGIF1 functions as a tumor suppressor in pancreatic ductal adenocarcinoma
A prominent function of TGIF1 is suppression of transforming growth factor beta (TGF‐β) signaling, whose inactivation is deemed instrumental to the progression of pancreatic ductal adenocarcinoma (PDAC), as exemplified by the frequent loss of the tumor suppressor gene SMAD4 in this malignancy. Surpr...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601038/ https://ncbi.nlm.nih.gov/pubmed/31268604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101067 |
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