Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia

Cancer cachexia is characterized by extreme skeletal muscle loss that results in high morbidity and mortality. The incidence of cachexia varies among tumor types, being lowest in sarcomas, whereas 90% of pancreatic ductal adenocarcinoma (PDAC) patients experience severe weight loss. How these tumors...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Parajuli, Parash, Kumar, Santosh, Loumaye, Audrey, Singh, Purba, Eragamreddy, Sailaja, Nguyen, Thien Ly, Ozkan, Seval, Razzaque, Mohammed S., Prunier, Céline, Thissen, Jean-Paul, Atfi, Azeddine
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054474/
https://ncbi.nlm.nih.gov/pubmed/29920276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.05.026
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