Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia

Cancer cachexia is characterized by extreme skeletal muscle loss that results in high morbidity and mortality. The incidence of cachexia varies among tumor types, being lowest in sarcomas, whereas 90% of pancreatic ductal adenocarcinoma (PDAC) patients experience severe weight loss. How these tumors...

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Gepubliceerd in:Dev Cell
Hoofdauteurs: Parajuli, Parash, Kumar, Santosh, Loumaye, Audrey, Singh, Purba, Eragamreddy, Sailaja, Nguyen, Thien Ly, Ozkan, Seval, Razzaque, Mohammed S., Prunier, Céline, Thissen, Jean-Paul, Atfi, Azeddine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054474/
https://ncbi.nlm.nih.gov/pubmed/29920276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.05.026
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